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People with certain versions of immune system genes, known as human leukocyte antigen (HLA) genes, are at higher risk of developing type 1 diabetes. Several HLA types increase the risk of the autoimmune disorder, but one genetic variant, known as "HLA-DR3-DQ2," exposes a form of the GAD protein (GAD65) to the immune system on the surface of beta cells, according to the statement. This triggers the immune system to produce antibodies against the protein and target the beta cells for destruction. christian lifestyle shirts It’s the FDA’s first approval of an "interchangeable" biosimilar, a near-copy of an injected biologic medicine that’s manufactured inside living cells. It could save diabetics and health plans millions of dollars annually and encourage other drugmakers to create more biosimilar medicines. Health data firm IQVIA projects U.S. savings from increasing use of biosimilars from 2020 through 2024 will top $100 billion. christian lifestyle shirts "Dental procedures are only one cause of infective endocarditis, and bacteria can get into the bloodstream simply during the course of daily life - for example through chewing or tooth brushing," said Dr. Tom Cahill, co-author of an accompanying editorial and a researcher at Oxford Heart Centre in the UK. christian lifestyle shirts Infective endocarditis is a rare but severe disease that kills one in five people hospitalized for the condition and has a five-year mortality rate of 40 percent, researchers note. christian lifestyle shirts

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